Doctor and Patient


How to initiate treatment with ZILBRYSQ

Doctor and Patient


Enroll in the ZILBRYSQ REMS

Before prescribing ZILBRYSQ to patients, healthcare providers must become certified in the ZILBRYSQ REMS (Risk Evaluation and Mitigation Strategy), which is intended to mitigate the risk of serious meningococcal infections.

Check the vaccination schedule to determine if it is necessary to complete or update the meningococcal vaccination series for your patient.

Vaccinate patients against meningococcal infection according to current ACIP recommendations at least 2 weeks prior to starting ZILBRYSQ.1

To learn more or become certified, please visit or call 1‑877‑414‑8353.


Complete the ONWARD™ Start Form to prescribe


To get an eligible patient started, complete the ONWARD Start Form (either electronically or by filling out the PDF and faxing it to ONWARD). ONWARD can collect the patient’s HIPAA authorization electronically, if needed.



Your patients are ready with ONWARD

ONWARD helps patients experience the benefits of ZILBRYSQ by providing education and support for eligible patients from initiation through continuation of treatment with services such as*:

  • A 24-hour turnaround time from intake to prescription triage with a completed Start Form (includes Financial Assistance eligibility assessment)
  • A dedicated Care Coordinator to help eligible patients start and stay on their prescribed treatment. The Care Coordinator can address patient questions about vaccination, self-injection, and affordability. Additionally, the Care Coordinator is able to communicate with patients using their preferred channel (phone, video chat, email, and text)
  • A demonstration device and refresher injection coaching with a Care Coordinator through video chat to help them prepare to self-administer ZILBRYSQ. Patients can find the full list of steps in the Instructions for Use

ONWARD is provided as a service of UCB and is intended to support the appropriate use of UCB medicines. ONWARD may be amended or canceled at any time without notice. Some program and eligibility restrictions may apply.

ONWARD does not provide medical advice and does not replace the care of the healthcare provider. Care Coordinators will refer patients to their healthcare provider for any treatment-related questions.



  1. ZILBRYSQ [Prescribing Information]. Smyrna, GA: UCB, Inc.